2020 St. Mary's Neurology Conference Program Schedule

Learn more about & register for the 2020 St. Mary's Neurology Conference

8:00

McCord Smith, M.D.
Neurologist, Vascular Neurologist & Neurohospitalist (retired)
St. Mary's Health Care System

Welcome

8:10

Bradley G. Phillips, Pharm.D., BCPS, FCCP
Millikan-Reeve Professor, Department of Clinical Administrative Pharmacy
Founding Director, Clinical and Translational Research Unit
Co-Chair, Biomedical Institutional Review Board, Office of the Vice President for Research
Department Head, Department of Clinical and Administrative Pharmacy
University of Georgia, Athens, GA

Georgia CTSA: Improving Heath in Georgia and Beyond

Objectives:

Understand resources, collaboration, and expertise available through the Georgia CTSA to advance neurology research across Georgia.
Discuss CTSA supported research and the opportunities to help lead ongoing and future neurology clinical trials.
Discuss how to apply for unique funding opportunities that support research studies in neurology

8:40

Elizabeth Sekul, M.D.
Associate Professor, Department of Neurology
Associate Professor, Pediatrics and Child Neurology
Augusta University, Augusta, GA

Spinal-muscular atrophy: Clinical Perspectives and Treatment Success with Targeted Gene Therapy

Objectives:

Review the clinical aspects of SMA
Discuss targeted gene therapy
Discuss recent advances in and approvals of gene therapy

9:25

Richard Steet, Ph.D.
Director of Research and Head of the JC Self Research Institute Greenwood Genetic Center (GGC),
Adjunct Research Professor, Department of Genetics and Biochemistry, Clemson University
Clinical Professor, Department of Cell Biology & Anatomy
University of South Carolina School of Medicine

Pushing the Nuclear Envelope: Functional Impact of LMNB1 Missense Variants in Patients with Microcephaly

Objectives:

Gain insight into the neurological manifestations associated with mutations in nuclear lamina genes
Discuss how different missense variants in the LMNB1 gene impact the function of the lamin B1 protein and the nuclear envelope
Appreciate the expanding roles of lamin B1 and the nuclear envelope in the regulation of gene expression and neuronal differentiation

9:55 Break

10:15

Kevin McCully, Ph.D., FACSM, FNAK
Professor, Department of Kinesiology
(Exercise Science Programs)
Director, Exercise Muscle Physiology Laboratory
University of Georgia, Athens, GA

Skeletal Muscle Dysfunction in Multiple Sclerosis and its Functional Consequences

Objectives

Describe muscle mitochondrial capacity and muscle specific endurance in people with MS
Characterize the relationship between muscle function and walking performance in people with MS
Discuss the influence of body weight support treadmill and functional electrical stimulation training on muscle function and walking performance in people with mobility limited MS

11:00

Tarkeshwar Singh, Ph.D.
Assistant Professor, Department of Kinesiology and Division of Neuroscience
Director, Sensorimotor Neuroscience Laboratory
Co-Director, Biomechanics Laboratory
University of Georgia, Athens, GA

Potential Links Between Visual Deficits and Postural Instability in Parkinson’s Disease

Objectives:

Identify signatures of visuomotor deficits in Parkinson’s disease
Understand the role of impaired postural reflexes on postural instability in Parkinson’s disease
Discuss potential neural mechanisms of visual deficits that could contribute to impaired postural reflexes in Parkinson’s disease

11:30 Lunch

12:30

Shelley A. Nuss, M.D.
Campus Dean
Campus Associate Dean for Graduate Medical Education
AU/UGA Medical Partnership, Athens, GA

Alzheimer's: The Forgotten Disease

Objectives:

Describe the scope of Alzheimer's disease
Review the signs and symptoms of Alzheimer's disease
Discuss the process of diagnosing Alzheimer's disease
Discuss the current state of treatment for Alzheimer's disease

1:15

Gerald Warren Hart, Ph.D.
Georgia Research Alliance William Henry Terry, Sr. Eminent Scholar in Drug Discovery
Professor of Biochemistry and Molecular Biology, Complex Carbohydrate Research Center
University of Georgia, Athens Ga.

Roles of the Nutrient Sensor, O-GlcNAc, in Neurodegeneration

Objectives:

Understand the many roles that O-GlcNAc cycling plays in neuronal development and functions
Appreciate the importance of the crosstalk between O-GlcNAc and Phosphorylation to the etiology of Neurodegnerative Disease
Realize the potential for new avenues of drug discovery revealed by fundamental research on O-GlcNAc in the brain

2:00 Break

2:15

Michael Tiemeyer, Ph.D.
Distinguished Research Professor and Co-Director
Complex Carbohydrate Research Center,The Department of Biochemistry & Molecular Biology
University of Georgia, Athens, GA

Glycobiology of the Choroid Plexus in Alzheimer’s Disease

Objectives:

Describe glycomic changes in Alzheimer’s Disease models
Appreciate the importance of epithelial protein glycosylation for regulating inflammatory responses
Translate principles of epithelial glycosylation to pathophysiologic mechanisms in Alzheimer’s Disease animal and cellular models

2:45

David C. Hess, M.D.
Dean, Medical College of Georgia
Executive Vice President for Medical Affairs and Integration
Presidential Distinguished Chair
Augusta University, Augusta, GA

Summary